The microRNA miR-196b acts as tumor suppressor in Cdx2 driven acute myeloid leukemia

Acute myeloid leukemia (AML) is characterized by high mortality, underlining the necessity for identifying tumor suppressors that counteract the leukemogenic potential of bona fide oncogenes such as the homeobox genes HOXA9 and CDX2 . Homeobox genes are aberrantly expressed in the majority of