Surgical Correction of the Apert Craniofacial Deformities
2002
Apert first utilized the term acrocephalosyndactyly in 1906 to describe a foreshortened, tower-shaped cranial malformation associated with syndactyly of all four extremities. Just over 300 such patients have been described in the literature. The syndrome occurs in 1 in 160,000 live births. More recently, Cohen utilized an indirect method and showed that Apert syndrome represented 4% of all the cases of craniosynostosis for 13.7 cases per 1,000,000 live births.1,2
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