The Potential of Cnidium officinale Makino as the Component of Gamgungtang to Induce the PhaseII Enzyme in vivo

The activity of phase II enzyme in the liver of mice was examined following the application of Cnidium officinale Makino aqua-acupuncture solution (COMAS). The application of COMAS to mice for 7 days increased quinone reductase(QR) activity. The glutathione S-transferase(GST) activity was also increased with COMAS. A greater increase was observed in the glutathione(GSH) levels than in the QR and GST activities.