Synthesis and Antimicrobial study of Rare Earth Complexes of Schiff Base Derived from 4-Amino Benzoic Acid
2019
Schiff base was prepared by using 4-amino benzoic acid and ortho-vanillin, namely(E)-4-((2-hydroxy-3-methoxybenzylidene)amino)benzoic acid. Schiff base and its complexes prepared by using nitrates of Cerium, Gadolinium and Dysprosium. Synthesized Schiff baseand complexes were structurally characterized by UV, IR, NMR, HRMS, TGA and elemental analysis. Structural characterization shows 1:2 metal to ligand ratio in the complexes with thecoordination of water molecule. The synthesized Schiff base and complexes were screened for their biological activity against bacterial species Gram –ve bacteria (Escherichia coli), Gram+ve bacteria (Staphylococcus aureus) and fungi (aspergillusniger).
Keywords: 4-amino benzoic acid; Rare earth; Schiff base and Antimicrob
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