Investigation of clinical features and resistance of methicillin-resistant Staphylococcus aureus in general hospital

2011 
OBJECTIVE To investigate the epidemiological characteristics and resistance of Methicillin-resistant Staphylococcus aureus(MRSA) in General Hospital,in order to make reference for infection control and clinical medication.METHODS A retrospective investigation method was used to collect data of 119 MRSA cases,then analyzing the clinical data and drug sensitivity test.RESULTS The community-associated MRSA and hospital-acquired MRSA infections were mainly on the lower respiratory tract position.63.03% were Healthcare-associated MRSA.There was significont difference in age,the length of days,invasive operation and the basic diseases.HA-MRSA had significantly higher resistance rate than that of CA-MRSA in clindamycin,erythromycin,tetracycline,and so on.CONCLUSION CA-MRSA and HA-MRSA cases differ demographically and clinically.The key measures to prevent infection of hospital-associated MRSA are monitoring key departments and susceptible patient,taking effective disinfection,reducing invasive procedures,using antibiotics drugs rationally.
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