Comparative studies on Synthesis of 2-Chloro-N-(2, 5-Dihydro-1, 3, 4-Thiadiazol-2-Yl) Acetamide using Microwave irradiation and Conventional techniques and their Antioxidant activity.

The advantages of Microwave irradiation technology in the field of organic chemistry have been long known as it facilitates accelerated reaction rates, higher yields with relatively less power consumption than classical techniques. The presented study compares aspects like reaction time and percentage yield of various 2- amino-1, 3, 4-thiadiazole derivatives when synthesized by both, conventional as well by microwave irradiation along with their characterization using techniques such as FTIR and HPLC. They have a very promising role in the field of medicinal chemistry owing to their anti-cancer and anti-fungal properties The study also aims to evaluate biological activity of the compounds a simple and inexpensive technique making use of 2,2-Diphenyl-1- picrylhydrazyl(DPPH) to establish their worth as potential anti-oxidants . Thus this combination of faster synthesis and cost effectiveness can significantly reduce the cost of production of various pharmaceutical products containing thiadiazole and/or its derivatives which are known to be clinically potent.