THE ALTERATON IN THE LEVEL OF SOLUBLE HLA I CLASS MOL- ECULES IN THE SERUM OF PATIENTS WITH HEPATITIS B AND C

Ðanoâiðeiua aioeaaiu HLA I eeanna (sHLA-I) ia-iaðoaeaiu âi iiiaeo aeieiae÷aneeo aeeaeinoyo, â o. ÷.â nuâiðioea e ieacia eðiâe, neþiiie aeeaeinoe, iaðe-oiiaaeuiuo aeaeecaoao e ii÷a [10]. Onoaiiâeaii, ÷oicia÷eoaeuiua eiee÷anoâa sHLA-I naeðaoeðoþony aeoe-âeðiâaiiuie eeioioeoaie eae in vitro, oae ein vivo.Aeoeâaoey iiaeao iðienoiaeou â ðacoeuoaoa âicaae-noâey ieoiaaiiâ e ðacee÷iuo aioeaaiiâ [4, 9]. Iieaca-ii, ÷oi iieaeoeu sHLA-I yâeyþony iðiaoeoaie iðioai-eeoe÷aneiai iouaieaiey io iaiaðaiu e/eee aeuoaðia-oeâiiai nieaeneiaa iÐIE. Iieaeoeu sHLA-I iiaooiiaoeeðiâaou ðaaeoeâiinou oeoioiene÷aneeo O-eeaoiee noeioeeðiâaou aiiioic â oneiâeyo in vitro, iiaaaðaee-âay oieaðaioiinou. Iie iiaoo nâycuâaouny n CD8-iiea-eoeaie ia iiâaðoiinoe O-eeioioeoiâ, iðaiyonoâoy