Carpal tunnel syndrome in inherited neuropathies: A retrospective survey

Introduction: This survey was conducted to evaluate carpal tunnel syndrome (CTS) symptom severity, functional status and outcome of CTS therapies in patients with inherited neuropathies. Methods: Validated questionnaires were used to compare symptom severity and functional status in patients with and without a diagnosis of CTS and a diagnosis of an inherited neuropathy. Results: 309 patients with inherited neuropathies participated in this study. The CTS symptom severity score (SSS),was found to be the most useful tool in assessing CTS severity in patients with inherited neuropathy. Splint therapy and surgery were associated with significant improvement in carpal tunnel symptoms as measured through the SSS. Discussion: This study provides an insight into the assessment of CTS symptom severity and patient reported outcomes to CTS therapy in individuals with inherited neuropathies. The SSS appears useful for evaluation of CTS symptoms and of patient reported outcomes following CTS interventions in individuals with inherited neuropathies. This article is protected by copyright. All rights reserved.