The Opening of ATP-Sensitive K+ Channels Protects H9c2 Cardiac Cells Against the High Glucose-Induced Injury and Inflammation by Inhibiting the ROS-TLR4-Necroptosis Pathway

Weijie Liang,Meiji Chen,Dongdan Zheng,Jianhao Li,Mingcai Song,Jianqiang Feng,Wenzhu Zhang,Jun Lan

The Opening of ATP-Sensitive K+ Channels Protects H9c2 Cardiac Cells Against the High Glucose-Induced Injury and Inflammation by Inhibiting the ROS-TLR4-Necroptosis Pathway

2017

Weijie Liang
Meiji Chen
Dongdan Zheng
Jianhao Li
Mingcai Song
Jianqiang Feng
Wenzhu Zhang
Jun Lan

Background/Aims: Hyperglycemia activates multiple signaling molecules, including reactive oxygen species (ROS), toll-like receptor 4 (TLR4), receptor-interacting

Keywords:

TLR4
Inflammation
Cell signaling
Biochemistry
Necroptosis
Biology
Receptor
Reactive oxygen species
Diabetes mellitus
high glucose

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