Biobased Nanohydrogels for Controlled Drug Delivery

Advances in biobased polymers have great considerable attention leading to the evolution of various novel drug delivery systems (DDS). The biocompatibility and biodegradability of these biopolymers, coupled to the large variety of chemical functionalities make them a promising carrier for DDS. The encapsulation of drugs using high molecular weight polymers can improve significantly both tumour targeting and therapeutic efficacy due to the improved permeability and water retention behaviour. However, polysaccharide-based nanohydrogels are prepared by reinforcing different nanomaterials in polysaccharides matrix for drug delivery applications. Further, the drugs release efficiency of biobased nanohydrogels can be enhanced, when tailor-made carbon quantum dot and specific nanostructured materials are reinforced to the specific materials. In this chapter, the preparation and characterization of different biobased nanohydrogels are discussed with suitability of their applications as potential drugs transporter. Moreover, the toxicity and stability of biobased nanohydrogels are studied after encapsulation of various drugs. The present chapter aims to explore the possibilities of safe and controlled release of various therapeutic drugs with the help of different biobased nanohydrogels.