Clinical efficacy of propofol and Ketofol anaesthesia with butorphanol by constant rate infusion using fluid bag technique in dogs

Twelve healthy mongrel dogs were included in the study and divided into two equal groups. All the patients were sedated with xylazine at 2 mg/kg b.wt. Group A was induced with propofol @4 mg/kg and Group B with Ketofol (1:1) @ 4 mg/kg by intravenous bolus administration. Maintenance was carried out by constant infusion of anaesthetic drugs at 6 mg/kg/hr at 5 ml/kg/hr flow rate in both the groups. Anaesthesia was maintained with fluid bag technique. Depth of anaesthesia was satisfactory in both the groups however dogs from Group A showed longer recovery time. Heart rate, rectal temperature and respiratory rate showed statistical difference (p< 0.05) between the groups but the values were within normal limits. On the basis of clinical and physiological observations, combination of ketamine-propofol-butorphanol was found to be satisfactory for maintenance of anaesthesia in canines.