HLA antigen in three types of glomerulonephritis.

Abstract HLA antigens were studied in 98 patients with glomerulonephritis. No significant differences in the frequency of HLA antigens from normal individuals were found in focal and segmental glomerulosclerosis. Conversely, in membranoproliferative glomerulonephritis with dense deposits, the frequency of HLA B7 was increased (44 vs 19% in 591 healthy controls) although not significantly. In glomerulonephritis with IgA mesangial deposits, BW35 was present in 48% of 29 patients compared to 18% in the control group ( P P P