Systematic review and verification of preventive effects of soy constituents on lifestyle-related diseases: effects of ingesting soy isoflavones on bone turnover markers in menopausal women and blood pressure in adult humans: systematic review and meta-analysis of randomized controlled trials (Part III).

Recent growing interest in health and diet has led to an increased assessment of the health eff ects of soy foods and their functional components. However the con‑ sensus on their eff ectiveness has not been achieved so far. In order to propose the appropriate intake of the functional components in the soy foods this study was aimed to 1 examine the eff ects of the functional components of soy foods on pre‑ vention of life style‑related diseases via systematic review and meta‑analysis of the related articles 2 survey the labeling and the contents of functional components of soy in the health foods. This year we performed one meta‑analysis to clarify the eff ect of soy isofl avone supplements on bone turnover markers in menopausal women and another to clarify the eff ect of soy isofl avone extract supplements on blood pressure in adult humans. PubMed CENTRAL ICHUSHI CNKI up to June 2009 were searched for published articles of randomized placebo‑controlled trials reporting the outcomes of soy isofl avone supplements on bone turnover markers (e.g. urinary deoxypyridinoline (DPD serum bone alkaline phosphatase (BAP or serum osteocalcin (OC in menopausal women and blood pressure (BP in adult humans. Meta‑analysis of 10 trials including 887 menopausal women revealed that daily in‑