Multidisciplinary Approach on Characterizing Composites of Vinpocetine and Crospovidone Obtained by Solid State Activation

Dritan Hasa,Dario Voinovich,Beatrice Perissutti,Alois Bonifacio,Mario Grassi,Erica Franceschinis,S. Dall’Acqua,M. Speh,J. Plavec

Multidisciplinary Approach on Characterizing Composites of Vinpocetine and Crospovidone Obtained by Solid State Activation

2010

Dritan Hasa
Dario Voinovich
Beatrice Perissutti
Alois Bonifacio
Mario Grassi
Erica Franceschinis
S. Dall’Acqua
M. Speh
J. Plavec

The poorly-soluble Vinpocetine was successfully coground with micronized crospovidone in a planetary mill, which allowed an enhancement of bioavailability through a solid-state activation. [...]

Keywords:

Solid-state
Bioavailability
Organic chemistry
Chemistry
Vinpocetine
Chemical engineering
Pharmacology

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