Continuous giggling and autistic disorder associated with hypothalamic hamartoma [Published with videosequences.]
2003
Introduction The syndrome of hypothalamic hamartoma and epilepsy is distinguished by early-onset drug resistant seizures - mainly gelastic seizures, partial complex seizures, and drop attacks - linked to significant cognitive and behavioural disturbances [1-3]. Intrinsic epileptogenicity inside the hamartomas has been demonstrated by means of stereo-EEG and depth recordings [3-5] and ictal SPECT [5-7]. [...]
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