New pyridone compounds or pharmaceutically acceptable salts thereof, process for the preparation thereof and pharmaceutical composition comprising the same for treatment or prevention of cancer
2010
PURPOSE: A pharmaceutical composition containing a novel pyridine compound for treating cancer is provided to suppress tumor cells as a HDAC inhibitor. CONSTITUTION: A novel pyridine compound is denoted by chemical formula 1. In chemical formula 1, R1 is C1-4 alkyl, C2-4 alkenyl, non-substituted phenyl or phenol substituted with 1-3 R3, pyridinyl, thienyl, non-substituted naphthalenyl or halogen-substituted naphathalenyl; quinolinyl, indanyl; benzothiopheyl, furanyl or benzofuranyl; and R2 is hydroxy, C1-13 alkoxy or NHR4. A pharmaceutical composition for preventing or treating cancer contains pyridine compound of chemical formula 1 or pharmaceutically acceptable salt as an active ingredient.
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