Pathomorphological Changes in Coligranuloma in Layer Birds

A coligranuloma was diagnosed in two birds during routine necropsy examination. Necropsy examination revealed hard nodular growth on serosal surface of intestine, mesentery, oviduct and uterus. Histologically, nodular growth showed granuloma with heterophilic and lymphocytes infiltration. Necrotic area was surrounded by a collar of giant cells, macrophages and lymphocytes with a layer of fibroblast at periphery. Isolation of organism on MacConkeys agar revealed Escherichia coli.