Evaluation of the effectiveness of a polyhexanide and propyl betaine-based gel in the treatment of chronic wounds.

Abstract The objective of this multicenter observational clinical study was to evaluate the therapeutic effects of a polyhexanide and propyl betaine-based gel in the treatment of patients of every age, affected by chronic skin wounds. One hundred twenty-four patients (60% females, from 4-day-old to 91-year-old, mean age 59) were treated with polyhexanide/propyl betaine (Prontosan® Wound Gel, B. Braun) applied directly on the surface of the wound and in the possible undermining, in combination with a secondary dressing. At the baseline visit and at subsequent checks were evaluated the wound diameter and characteristics (the wound bed and the surrounding skin and edges appearance, level and type of exudate) and local pain at dressing change. The assessment and analysis between the initial visit and the final one showed the following results: the wound size and pain characteristics have decreased substantially and significantly (P