Electrophoretic enantioseparation of profens in water-methanol solutions using eremomycin as a chiral selector

The possibility of the electrophoretic enantioseparation of profens in water-methanol solution of eremomycin was demonstrated. The effect of the methanol content, phosphate buffer pH, and chiral selector concentration on enantioresolution was studied. Water-methanol background electrolyte was shown to provide better reproducibility of migration times and baseline stability compared to aqueous buffers. The time of analysis in nonaqueous conditions is less than 15 min.