Fractional CO2 laser for treatment of stress urinary incontinence

Abstract Objectives To evaluate the impact of trans-vaginal fractional CO 2 laser treatment on symptoms of stress urinary incontinence (SUI) in women. Study design Women clinically diagnosed with SUI preferring non-surgical treatment were recruited to the study. Fractional CO 2 laser system (MonaLisa T, DEKA) treatments were administered trans-vaginally every 4–6 weeks for a total of three treatments. Response to treatment was assessed at baseline (T1), at 3 months after treatment completion (T2) and at 12–24-month follow-up (T3) using the Australian Pelvic Floor Questionnaire (APFQ). The primary outcome was changes in reported symptoms of SUI. Secondary outcomes assessed included bladder function, urgency, urge urinary incontinence (UUI), pad usage, impact of urinary incontinence on quality of life (QOL) and degree of bothersome bladder. Results Fifty-eight women were recruited and received the study treatment protocol. Eighty-two percent of participants reported an improvement in symptoms of SUI at completion of treatment (mild to no SUI) (p =  Conclusions This study suggests that fractional CO 2 laser is a safe, feasible, and beneficial treatment for SUI and may have a role as a minimally-invasive alternative to surgical management.