CaO-MgO-SiO2-P2O5- based multiphase bio-ceramics fabricated by directional solidification: Microstructure features and in vitro bioactivity studies

Abstract In vitro activity is important when considering the choice of a multiphasic bioceramic scaffold as phases can dissolve or transform at different rates. The aim of this study is focused on the synthesis and in vitro analysis of multiphasic ceramics obtained from the melt by directional solidification. Depending on the growth rate of the new composition different bioactive phases coexist in the same sample: akermanite, monticellite, tricalcium phosphate and Nurse´s A phase, all of them with potential in the medical area as implant for bone or dental repair. With the knowledge of what and how phases dissolve first, it was possible to design materials to get porous scaffolds or more stable ceramics.