Chemical composition and osteogenerating properties of the bioactive coating on titanium alloy

Bioactive calcium-phosphate coating on Ti–6Al–4V titanium alloy was formed by plasma electrolytic oxidation (PEO). The osteogenerating properties of the obtained coating were assessed in vivo at fractures of the shaft of the femur of laboratory rats. The obtained PEO-coating accelerates osteogenesis and promotes the formation of a pronounced periosteal callus in the fracture area. The bone tissue growth on the surface of the implant was significantly accelerated by the presence of calcium phosphates in the chemical composition of the PEO-coating.