Weight gain since age of 20 as risk of metabolic syndrome even in non-overweight individuals

Purpose Metabolic syndrome (MetS), regardless of the presence of obesity, is known as a risk of diabetes and cardiovascular disease. Weight gain after age 20 reported to be associated with these diseases. Impact of the difference between the body mass index (BMI) at examination and BMI at age 20 (ΔBMIexa−20y) on MetS, especially in non-overweight individuals, remains to be elucidated.