Surveillance on epidemic cerebrospinal meningitis in Gansu from 2005 to 2008

Objective: To explore the epidemic feature,distribution and drug resistance of the epidemic cerebrospinal meningitis(ECM)barrier and adopt preventive measure.Methods:From 2005 to 2008,according to diagnostic code and principle of management for ECM,we carried out serologic identification,biochemical test and detection about distribution barrier and drug resistance.Results:Collecting 102 throat swab and 63 cerebrospinal fluid from ECM cases,621 cerebrospinal fluid from people who contacted ECM patient intimately,2528 throat swab from healthy population.62 Nm strains were detected.Among them,36 Nm strains were tested about drug sensitivity.The result showed that cefotaxime,chloromycetin and ciprofloxacin with the sensitivity rate of 100%.Other 7 antibiotics with the sensitivity rate is 30.56% to 97.22%.Conclusion: In recent years,group Nm A of ECM is still very important part in ECM cases.The group Nm C is increasing.Drug resistance stains is growing in quantity year after year.The strong suggestion is given to clinical practice in rational use of antibiotics based on the drug resistance.