Improvement of T1 Contrast in Whole-brain Black-blood Imaging using Motion-sensitized Driven-equilibrium Prepared 3D Turbo Spin Echo (3D MSDE-TSE)

: We demonstrated a new scheme for performing the T1-enhanced whole-brain black-blood imaging pulse sequence using motion-sensitized driven-equilibrium prepared 3-dimensional (3D) turbo spin echo (MSDE-TSE) with anti-driven-equilibrium post pulse. The use of an anti-driven-equilibrium pulse considerably improved the T1 contrast of MSDE-TSE black-blood images. This sequence can be used for whole-brain 3D volumetric T1-weighted black-blood imaging and may improve the accuracy of anatomical localization for certain brain lesions.