Abstract 17141: Assessment of Dyssynchrony as an Indicator of Right Ventricular Free Wall Function by Gated Blood Pool SPECT (GBPS) in Patients undergoing LVAD Implantation

Introduction: RV function affects prognosis after LVAD, but is difficult to assess by conventional imaging due to complex geometry. Regional RV free wall (RVFW) function may be particularly important after LVAD due to septal shift toward the decompressed LV. We have previously shown feasibility of pre-LVAD GBPS (automated, count-based, without geometric assumptions) assessment of the RV, and the additive value of regional over global dysfunction. Here, we explored the utility of RVFW dyssynchrony assessment using phase analysis as a quantitative predictive parameter of RV regional function. Methods: GBPS was performed using standard procedure on 25 patients awaiting LVAD. Global and regional RV function was assessed. The phase standard deviation (PSD) of the RVFW (non-septal portion of RV) was generated automatically. RV failure was defined as requiring RV assist device or requiring greater than 14 consecutive days of postoperative inotropic support after LVAD implant. Results: Of 25 consecutive patients ...