THE SYNTHESIS OF NEW ACYCLIC ANALOGS OF 3-PHENACYLURIDINE AND COMPARATIVE EVALUATION OF THEIR IN VIVO BIOLOGICAL ACTIVITY

2020 
New structural analogs of 3-phenacyluridine were obtained as a result of N(3)-alkylation of 1-(2-acetoxyethyl)- and 1-(2-acetoxyethoxymethyl)uracil. Biological studies of the title compounds in an acute in vivo experiment did not reveal their hypnotic properties and ability to enhance the effects of diazepam and chloral hydrate.
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