Other Antitumor Antibiotics

Mithramycin, or aureolic acid, is an antitumor antibiotic derived from the species Streptomyces plicatus. At present, it is not a part of the therapeutic armamentarium of any specific malignancy. At one time, however, it played a significant role in the management of embryonal cell carcinoma of the testes. Currently, mithramycin is used chiefly in the treatment of cancer-related hypercalcemia.