The Synthesis and Evaluation of anti-tubercular activity for some new 4-{4-[(hydrazinylmethoxy) (hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one novel Derivatives.
2020
A new series of 4-{4-[(hydrazinylmethoxy)(hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one were designed and synthesized in order to evaluate their anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that; synthesized compounds showed the good to moderate anti-tb activities.
Keywords: Quinoxaline, ortho-phenylenediamine and hydrazinehydrate.
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