Deep vein thrombosis in a patient of adenomatous polyposis coli treated successfully with aspirin: A case report

Venous thromboembolism is an important cause of hospital acquired morbidity and mortality (1). Its association with adenomatous polyposis coli is a rare event (2, 3). Malignancy or major operative procedure associated with colonic polyp may predispose to thromboembolic event (2). There has been previously published few reports of diarrhea associated with deep vein thrombosis (4-6). Etiology of diarrhea in those cases was unrelated to colonic polyp. However, association of deep vein thrombosis with non-malignant colonic polyp presenting with diarrhea is an extremely rare event with a report of only one case in previous English literature (3). Mainstay of therapy of deep vein thrombosis is anticoagulation. However, fatal bleeding episode following anticoagulation in our patient lead to withdrawal of anticoagulation therapy. The patient was treated successfully with low dose aspirin therapy (75mg/day) with complete resolution of thrombus.