Comportement des mastocytes chez les rats traités au perchlorate de potassium

The authors study the number of mastocytes and the percentage of degranulated types in rats treated with potassium perchlorate. This product has an antithyroid activity. An increase in absolute number of mastocytes in the thyroid gland of treated animals is shown. There is also an increase of degranulated types of these cells. In the other organs (skin, liver, lungs) a decrease in absolute number of mastocytes is observed with a concomitant increase of degranulated types. The results are discussed according to the literature.