Therapeutic Effects of Inhaled Budesonide in Treating Bronchiolitis (22 Cases)

2003 
Objective:To evaluate the therapeutic effects of inhaled budesonide nebulising suspension on bronchiolitis in children. Methods:44 infants, 2-18 months of age, needing hospital treatment because of bronchiolitis, were divided randomly into two groups. All received the same general treatment. 22 infants in the control group received general therapy only, 22 infants in the treating group received extra treatment with inhaled budesonide, 500 μg twice per day, administered via a nebulizer. The clinical effects of budesonide were evaluated in both groups. Results:The treated group showed a rapid improvement in respiratory symptoms (such as cough, wheezing) with a cure rate of 90.91%. The cure rate of the control group was 63.64%. There was significant difference between the two groups ( P 0.01). Conclusion:The results of study indicate that inhaled budesonide in nebulized form treating bronchiolitis may remarkably reduce course of treatment and improve curative effect with convenience in use and few side-effects.
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