Hospital usage of TOXBASE in Great Britain: temporal trends in accesses 2008 to 2015

Aim:To examine temporal trends in accesses to the UK’s National Poison Information Service’s TOXBASE database in Britain.Methods:Generalized additive models were used to examine trends in daily numbers of accesses to TOXBASE from British emergency departments between January 2008 and December 2015. Day-of-the-week, seasonality and long-term trends were analysed at national and regional levels (Wales, Scotland and the nine English Government Office Regions).Results:The long-term trend in daily accesses increases from 2.8 (95% confidence interval (CI): 2.6–3.0) per user on 1 January 2008 to 4.6 (95% CI: 4.3–4.9) on 31 December 2015, with small but significant differences in population-corrected accesses by region (p < 0.001). There are statistically significant seasonal and day of the week patterns (p < 0.001) across all regions. Accesses are 18% (95% CI: 14–22%) higher in summer than in January and at the weekend compared to weekdays in all regions; there is a 7.5% (95% CI: 6.1–8.9%) increase between Frida...