Methylene blue induced methemoglobinemia with acute kidney injury in a glucose-6-phosphate dehydrogenase-deficient patient

: Our case was treated with methylene blue for symptomatic nitrobenzene poisoning. After which he developed methemoglobinemia with acute kidney injury due to hemolysis and on further testing, he was found to be glucose-6-phosphate dehydrogenase (G6PD) enzyme deficient. Thus, afterward, the patient was treated with only available mode of treatment as repeated blood transfusions and ascorbic acid with dialysis support to which the patient responded. Thus, it is important to evaluate for the G6PD deficiency where methylene blue treatment is planned as an antidote to nitrobenzene compounds poisoning.