Preparation of [carboxy‐13C]4‐nitrophenylacetic acid

Reaction of sodium [13C]cyanide with excess benzyl chloride gave ∼75% utilization of the isotope. Subsequent nitration, isomer separation and hydrolysis of the nitrile gave the required carboxy-labelled 4-nitrophenylacetic acid. Copyright © 2005 John Wiley & Sons, Ltd.