Synthesis and antiaggregative activity of a new RGDF mimetic

m-[4-Oxo-4-(piperazin-1-yl)butyrylamino)benzoyl-D,L-β-(3,4-methylenedioxyphenyl)-β-alanine, a new mimetic of the peptide RGDF, was synthesized. This compound inhibited ADP-induced platelet aggregation in human blood plasma enriched with platelets with IC50 = 3.5 × 10–8 M.