Localsympatheticstimulationnot onlyhavelocaleffectsinpatients withRaynaud'sphenomenon

OBJECTIVE : Many other organs and system can be affected in the course of Pri - mary Raynaud's Phenomenon (RP). Simultane - ously increased vasospasm in the pulmonary vascular bed may likely affect the pulmonary function. Therefore, we investigated the effect of Raynaud's phenomenon on the respiratory func - tions in this study. PATIENTS AND METHODS: Between March 2014 and December 2014, 30 patients with the di - agnosis of PRP more than two years and 32 age- sex matched healthy controls were enrolled into this study. Cold stimulation test (CST) was per - formed. Pulmonary function test were performed following 30 minutes after CST and spirometric measurements were calculated. RESULTS: There were no statistically signifi - cant differences between two groups regarding their demographic and clinical data. Mean dura - tion of symptoms from onset to present was 3.01 ± 1.05 years. Patients with Primary RP had significantly lower FVC and higher FEV 1/FVC val - ues compared to the control groups ( p = 0.015 and p=0.045, respectively). CONCLUSIONS: We found that statistically significant decrease of FVC values in patients with Primary RP compared to the healthy con - trols could be a impaired innervation of pul - monary system and a predictor of pulmonary va - sospasm and/or pulmonary Raynaud's phenom - enon, which may develop in future periods.