Gamma-carbolines Tetrahydro.
1998
A compound of formula ** ** a N-oxide, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof, wherein: R1 is hydrogen, C1-6alkyl, aryl or C1-6alkyl substituted with aryl; R2 is each independently a halogen, hydroxy, C1-6alkyl, C1-6alkyloxy or nitro; n is 0, 1, 2 or 3; Alk is C1-6; D is a radical of formula wherein each X independently represents O, S or NR12; R3 is hydrogen, C1-6alkyl, aryl or arylC1-6alkyl; R4 is hydrogen, C1-6alkyl, C1-6alkyloxy, C1-6alkylthio, amino, mono- or di (C1-6 alkyl) amino, mono- or di (arylC 1-6 alkyl) amino; R5, R6, R7, R10, R11 and R12 are each independently hydrogen or C1-6 alkyl; R8 and R9 are each independently hydrogen, C1-6 alkyl or aryl.
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