Use of tetrahydroisoquinoline derivatives

The invention relates to the use of tetrahydroisoquinoline derivatives and relates to the use of compounds of a general formula (1) and salts thereof in the preparation of medicaments, in particular to the use in the preparation of novel anti-inflammatory and analgesic medicaments. The tetrahydroisoquinoline derivatives have the same or higher activity than ibuprofen and avoid gastrointestinal tract side effects of common nonsteroidal anti-inflammatory medicaments.