Imidazole-Promoted Synthesis of N-Substituted Phthalimide from N,N′-Disubstituted Ureas in Solventless Conditions.

Abstract A series of N-substituted phthalimides was synthesized by a thermal reaction between N,N′-disubstituted ureas and phthalic acid catalyzed by imidazole in solventless conditions. The products have been obtained in moderate to good yields (53–92%). Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.