Anti–inflammatory activity of the glandular extracts of Thunnus alalunga

Abstract Objective To evaluate the anti-inflamattory activity of Thunnus alalunga by both in vitro and in vivo methods. Methods Anti-inflammatory activity of the chloroform water extract of Thunnus alalunga was done by both in vitro and in vivo methods. In vitro method was done by human red blood cells membrane stabilization method (HRBC). In vivo evaluation was estimated on Wister albino rats. Acute toxicity studies were done on the extract and no toxicity was reported. Results The percentage protection exhibited by 300 mg/mL concentration was more when compared to the other ones. The 400 mg/mL concentration showed potent activity on comparison with the standard during in vivo evaluation. Conclusions In both means of estimation the extract of Thunnus alalunga was found to possess significant anti-inflammatory activity.