RELACIÓN ENTRE LOS FACTORES CLÍNICO PATOLÓGICOS Y ENFERMEDAD GANGLIONAR INGUINAL EN CÁNCER DE PENE

Determinar la relacion entre factores clinicopatologicos y enfermedad ganglionar inguinal en cancer de pene, en los pacientes del Instituto de Oncologia “Dr. Miguel Perez Carreno”. Estudio retrospectivo, descriptivo, transversal, de 76 pacientes con cancer de pene1995-2011. Un total de 76 pacientes, 20 (26,31%) entre los 51-60 anos, siendo el grupo etario con mayor incidencia; el estadio mas frecuentemente el IIIB con 23 casos (30,26%), histologia predominante carcinoma epidermoide 62 casos (81,57%); la invasion angiolinfatica positiva 37 pacientes y 19 casos (51,35%), presentaron metastasis ganglionar inguinal, y 31 casos (45,58%) sin invasion angiolinfatica 0% de metastasis. Grado histologico: Los tumores GI 41 de 76 casos (54%), el 29,2% (12 casos) se presento con metastasis inguinal, los tumores GII y GIII el 77% (17 casos), y 100% (5 casos) respectivamente; en relacion al (T), grado histologico y metastasis inguinales, los T1G1 fueron los mas frecuentes, con 22 casos, solo 1 de ellos con metastasis, de los T2, los T2G2 fue el de mayor frecuencia con 8 casos, 6 de ellos, con metastasis ganglionar inguinal, los T3G1, estuvo conformado por 10 pacientes, siendo el de mayor numero de pacientes, 5 de ellos presentaron metastasis ganglionar inguinal; el resto de T3 y T4 presentaron MT. El grado histologico asociado a la profundidad de invasion y la invasion linfovascular son factores predictivos importantes de enfermedad ganglionar en cancer de pene. (AU) To determine the relationship between the clinics pathological factors and the presence of inguinal nodal disease in penile cancer in patients view in the Oncology Institute Dr. Miguel Perez Carreno. Retrospective, descriptive and transversal investigation, with 76 patients with diagnostic of penile cancer view between the years 1995-2011. A total of 76 patients, 20 (26.31%) between 51-60 years old, and the age group with the highest incidence, stage IIIB more frequently with 23 cases (30.26%), squamous cell carcinoma predominant histology 62 cases (81.57%), positive angio lymphatic invasion in 37 patients and 19 (51.35%) had inguinal lymph node metastases, and 31 cases (45.58%) without groin metastases, as to histological grade, tumors GI 41 of 76 cases (54%), 29.2% (12 cases) presented with inguinal metastases, GII and GIII tumors 77% (17 cases), and 100% (5 cases) respectively, in terms of the (T), histological grade and metastatic inguinal T1G1 were the most frequent, with 22 cases, only 1 patient with metastasis, the T2, the T2G2 had the highest frequency of 8 cases 6 of them, with inguinal lymph node metastasis, the T3G1, consisted of 10 patients, with the largest number of patients, 5 of them presented inguinal lymph node metastasis, the rest of T3 and T4 showed metastases. The histological grade associated with the depth of invasion and lymph vascular invasion are important predictors of nodal disease in penile cancer. (AU)