Effect of Seasonal Changes on Serum Vitamin D Concentration

Vitamin D is essential for the formation and maintenance of strong and healthy bones. Vitamin D deficiency can occur from inadequate sun exposure, insufficient food intake, decreased absorption, abnormal metabolism or vitamin D resistance. This study aims to assess the status of 25 (OH) D in serum in different seasons in the population of the Polog region during the period of the year 2019, January-December. Serum 25 (OH) D concentration was measured by the Chemiluminescent method. The study included 997 subjects of different ages and genders who routinely determined the serum 25 (OH) D concentration. The largest number of subjects were tested in the period October-December, based on the obtained results the minimum values of 25 (OH) D was 4.87 ng/ml, where as at the age group >60 years with an average of 15.686 ± 7.6 ng/ml. During the fall and winter months, both sexes are at high risk of vitamin D deficiency corresponding to low serum 25 (OH) D levels.