Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Johannes Kettunen,Taru Tukiainen,Antti-Pekka Sarin,Alfredo Ortega-Alonso,Emmi Tikkanen,Leo-Pekka Lyytikäinen,Antti J. Kangas,Pasi Soininen,Peter Würtz,Kaisa Silander,Danielle M. Dick,Richard J. Rose,Markku J. Savolainen,Jorma Viikari,Mika Kähönen,Terho Lehtimäki,Kirsi H. Pietiläinen,Michael Inouye,Mark I. McCarthy,Antti Jula,Johan G. Eriksson,Olli T. Raitakari,Veikko Salomaa,Jaakko Kaprio,Marjo-Riitta Jarvelin,Leena Peltonen,Markus Perola,Nelson B. Freimer,Mika Ala Korpela,Aarno Palotie,Samuli Ripatti

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

2012

Samuli Ripatti and colleagues report a genome-wide association study for human serum metabolites using NMR of serum samples from over 8,000 Finnish individuals. They identify 31 loci associated with at least one of 216 serum metabolic measures.

Keywords:

Genomics
Metabolite
Genetics
Quantitative trait locus
Locus (genetics)
Genotype
Metabolome
Phenotype
Genome-wide association study
Biology
Population
Polymorphism (computer science)

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