Analysis of the biological tissue with the probe and method of use

The present invention relates to isolated enzymes obtained from the living tissue in a method having a high yield cells or cell populations with high biological activity and for its probes. In particular, the present invention relates to a method for the analysis of biological tissue, wherein, for two or more protein binding to a specific biological component, and each contains two or more components of the biological probe binding domain the isolated living tissue for analyzing the amount of binding for each probe in living tissue.