antiproliferative activity rich oligonucleotides gy method of use thereof for binding to nucleolin.

Use of a therapeutically effective amount of a rich oligonucleotide guanosine able to bind at least one protein or nucleolin binder G-rich oligonucleotides for the preparation of a pharmaceutical composition for inhibiting the proliferation of malignant cells, dysplastic and / or hyperproliferative a subject.