Intestinal nematode infections and efficacy study of oxantel-pyrantel pamoate among plantation workers.

Pyrantel has been demonstrated (Bumbalo et al., 1969; Desowitz et al., 1970; Hsieh, 1971) to be effective for treatment of Ascaris, hookworm and Enterobuis. Oxantel has been shown (Zaman and Sabapaty, 1975; Garcia, 1976; Lee et al., 1976; Rim et al., 1976) to be effective against Trichuriasis. A combined Oxantel-pyrantel salts has been shown (Rim et al., 1975; Lim, 1978; Dissanaike, 1978; Cabrera and Sy, 1978) to be highly effective against soil-transmitted helminthiasis, particularly Trichuriasis. Most of these studies were conducted on schoul children. The presents efficacy study of oxantel-pyrantel pamoate was among the working adult estate population of both sexes. This paper presents the results of study conducted at 4 different localities of the Dunlop Estates Group in Southern part of West Malaysia.