Na+/H+ exchange mediates meal-stimulated ileal absorption

Background. The ingestion of a meal increases water and electrolyte absorption the jejunoileum. Recent observations have implicated Na + -glucose cotransport as a primary mediator of meal-stimulated jejunal absorption. The current experiments tested the hypothesis that Na + /H + exchange is a major mediator of basal and meal-stimulated ileal absorption. Methods. Absorption studies (n=36) were performed on dogs with 25 cm ileal Thiry-Vella fistulas