multigene family. the major histocompatibility complex class II between the promoters of different members of Two DNA-binding proteins discriminate

onB2. TheGresidues thataffect DNA-proteininteractions whenmethylatedare indicatedontheDPAandDQAsequences. Filledarrowheadsindicate methylatedGresidueswhichinterfere stronglywithbinding, whereasopenarrowheadsrepresentweakinterference. Thearrowindicates a Gresidue at which methylation enhances binding.