Statin Monotherapy Attenuates Renal Injury in a Salt-Sensitive Hypertension Model of Renal Disease

José Mauro Vieira,L.T. Rodrigues,E. Mantovani,Humberto Dellê,Ana Lúcia Mattar,Denise Maria Avancini Costa Malheiros,Irene L. Noronha,Clarice Kazue Fujihara,Roberto Zatz

Statin Monotherapy Attenuates Renal Injury in a Salt-Sensitive Hypertension Model of Renal Disease

2005

José Mauro Vieira
L.T. Rodrigues
E. Mantovani
Humberto Dellê
Ana Lúcia Mattar
Denise Maria Avancini Costa Malheiros
Irene L. Noronha
Clarice Kazue Fujihara
Roberto Zatz

Background: Several salutary biological effects of statins have been described. We sought to investigate more closely the anti-inflammatory and antiproliferative effects of simvasta

Keywords:

Western blot
Simvastatin
Cell growth
Statin
Proliferating cell nuclear antigen
Transforming growth factor
Nitric oxide
Endocrinology
Internal medicine
Medicine
Diabetes mellitus
Disease
interstitial fibrosis
renal injury
salt sensitivity

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